13 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... • B12/Folate ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... Approach - MCV) ... Megaloblastic: Vitamin B12 ... #differential #diagnosis ... #causes #hematology
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
) Deficiency Clinical ... Diagnosis - Caine ... dysfunction and gait ... #Deficiency #diagnosis ... #criteria #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
ataxia (broad-based gait ... and retrograde amnesia ... #vitaminB1 #B1 # ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach ... e.g AEIOU ) or anuria ... require urgent nephrology ... creatinine (in 12 ... #nephrology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... #oncology #hematology ... #diagnosis #management
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #differential #diagnosis ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... Non-compressive Spinal Cord Causes ... myelopathy - Vit B12 ... #neurology #differential