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diagnosis differential management nutrition oncology rbc alkaline alp aplastic atlas bariatric bloodcell bypass cirrhosis cobalamin deficiencies fat fatrbc gastric gastroenterology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Megaloblastic: Vitamin ... B12 deficiency, ... Folate deficiency ... differential #diagnosis #causes ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Macrocytic RBC: Vitamin ... B12 or Folate deficiency ... Liver Disease, MDS ... differential #diagnosis #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... PRODUCTION • Vitamin ... B12 deficiency, ... Folate deficiency ... Differential #Diagnosis #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait ... Hyophosphatasia #hepatology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
RBC Mnemonic for Causes ... Folate (Fetus) and B12 ... Deficiency - Impairs ... Marrow Disorders (MDS ... Differential #Diagnosis #Hematology
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery Nutrient Deficiencies: • Most frequent in the malabsorptive surgeries
folate, iron, B12 ... • Persistent nausea ... years • Pervasive neurologic ... Gastroenterology and Hepatology ... gastroenterology #nutrition #Vitamin
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... well as varying clinical ... These causes could ... Satyendra Dhar MD
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Nutritional: vitamin ... B12 or folic acid ... deficiency • Exposure ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology
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