22 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait ... Phosphatase: • Other causes
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
) Deficiency Clinical ... Diagnosis - Caine ... dysfunction and gait ... #Deficiency #diagnosis ... #criteria #neurology
Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal
upward (cephalad) movement ... paralysis from spinal cord ... been observed in ALS ... #PhysicalExam #clinical ... video #umbilicus #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
ataxia (broad-based gait ... and retrograde amnesia ... #vitaminB1 #B1 # ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal Cord ... Motor Nerves: ALS ... : Acid maltase deficiency ... #differential #diagnosis ... #neurology
Opsoclonus-Myoclonus Ataxia Syndrome (OMAS) -Dancing eyes - dancing feet syndrome
 • Opsoclonus: ocular spontaneous, arrhythmic, conjugate
occurring in all ... caused by muscular ... Ataxia #Syndrome #clinical ... #video #neurology ... #gait
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
: CHF, valves, COPD ... ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS ... #causes #neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #differential #diagnosis ... #neurology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... & Fe Sucrose > alt ... restricted diet/deficiency ... /other causes • ... IBD #Algorithm #diagnosis