10 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Renal Disease, Liver ... (>100 fL) • B12 ... Deficiency • ... #MCV #Classification ... Algorithm #Causes #Hematology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Erythropoiesis (B12 ... in pernicious anemia ... • Refeeding syndrome ... Losses Non-renal ... #low #potassium
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
• Scleroderma renal ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia ... " • HELLP syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... #oncology #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical ... Whipple, vitamin deficiency ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... Differential #Subtypes #Classification
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... Workup: • Complete
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... - Compartment syndrome ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... #typea #typeb #classification
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
), sickle cell anemia ... aldosterone synthase deficiency ... antiphospholipid syndrome ... Diagnosis #High #Potassium ... #Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... disease • Prolidase deficiency ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia