11 results
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... differential #diagnosis #causes ... #neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
U: Symptomatic Uremia ... daily dialysis): ~12 ... Corrects uremia, ... Gently corrects uremia ... #managment #nephrology
Renal Replacement Therapy (RRT) Modalities

RRT Modalities in the ICU:
 • IHD (Intermittent HD):  3-5 hr
(Sustained low efficiency ... daily dialysis): ~12 ... Corrects uremia, ... Gently corrects uremia ... #managment #nephrology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS), NMJ disorder ... Differential #Diagnosis #causes ... #neurology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... Clinical Presentation ... breath, wasting, anemia ... Loss of teeth Anemia ... , or any other cause
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... HCO3)} Normal = 12 ... Renal failure (uremia ... #AcidBase #disorders ... Diagnosis #Summary #Nephrology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Infectious causes ... antibodies • Nutritional ... Deficiency: - ... diagnosis #management #neurology