15 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Dietary Deficiency ... and Folate Deficiency ... #Macrocytosis # ... #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
the most likely cause ... recovery also causes ... deficiency is present ... deficiency. ... #VitaminB12 #Folate
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Approach to Hypoproliferative ... Macrocytic Anemia ... • 812, Folate ... Deficiency • ... diagnosis #algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... • B12/Folate ... Deficiency • Aplastic ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
(Morphological Approach ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... differential #diagnosis #causes ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Megaloblastic: Folate ... deficiency, B12 ... deficiency, Orotic ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Folate Deficiency ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... (>100 fL) • B12 ... Folate Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... : • B12/folate ... #Hematology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Crohn's > UC Anemia ... If persistent macrocytosis ... • Supplement folate ... restricted diet/deficiency ... /other causes