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hematology differential algorithm causes workup macrocytic management oncology classification disease elevatedmcv macrocytosis microcytic pancytopenia aplastic approach arthritis atlas behcet bloodcell
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... inflammation) • Iron ... Megaloblastic: Folate ... deficiency, B12 ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Microcytic" • Iron ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Reticulocytes, MCV ... Iron, Ferritin, ... Deficiency • ... B12/Folate Deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... - Differential Diagnosis ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Iron deficiency ... disease - Vitamin B12 ... and/or folate deficiency ... #diagnosis #differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... - Differential Diagnosis ... Neutrophils - Low RBC Folate ... • Dietary Deficiency ... and Folate Deficiency
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
RBC turnover • Iron ... , B-12, or folate ... deficiency • ... • Hemolytic anemia ... Increase #Decrease #Diagnosis
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Iron deficiency ... , ↓ Ferritin Anemia ... deficiency + Chronic ... #diagnosis #differential ... #hematology #laboratory
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... : • MCV/RBC - ... #Deficiency #Anemia ... #ferritin #Fe #diagnosis ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Deficiency (Eg ... Malabsorption, Dietary Deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
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