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diagnosis hematology differential algorithm causes workup classification elevatedmcv macrocytosis microcytic pancytopenia approach atlas bariatric bloodcell bypass calculation deficiencies gastric index
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
inflammation) • Iron ... Infections Macrocytic ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
• Iron deficiency ... - "Macrocytic" ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC Folate ... • Dietary Deficiency ... and Folate Deficiency
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... #Anemia #differential ... diagnosis #algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... Iron, Ferritin, ... Reticulocytes • Iron ... Deficiency • ... B12/Folate Deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... #MCV #Classification
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... or Folate deficiency ... deficiency anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... erythropoietin (EPO), iron ... or B12 repletion ... substrate (e.g. iron ... Diagnosis #Workup #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron ... deficiency anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Deficiency (Eg ... Malabsorption, Dietary Deficiency ... #Microcytic #Anemia ... Algorithm #Causes #Hematology
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