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diagnosis differential hematology algorithm causes bariatric classification gastric nutrient pancytopenia vitamin calculation gastroenterology index morphologic neutropenia production reticulocyte supplementation surgery
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... inflammation) • Iron ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Reticulocytes, MCV ... Iron, Ferritin, ... Deficiency • ... B12/Folate Deficiency
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... Microcytic" • Iron ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... #MCV #Classification
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery Nutrient Deficiencies: • Most frequent in the malabsorptive surgeries
common are Vit D, folate ... , iron, B12 and ... years • Pervasive neurologic ... Phos, Ca+, Bl, B12 ... , Vit D, Folate,
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined ... deficiencies
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Deficiencies: ... consumption • Vitamin B12 ... • Folate deficiency
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
After Gastric Bypass ... cardiomyopathy) • Folate ... • Vitamin B12 ... Trace Minerals: • Iron ... #vitamin #nutrition
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
: Iron deficiency ... loss), Vitamin B12 ... , Folate • Hormone ... deficiencies: Chronic ... , G6PD deficiency
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