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diagnosis differential hematology algorithm bariatric bypass classification gastric nutrient pancytopenia vitamin ascorbicacid calculation elevatedmcv gastroenterology index macrocytic macrocytosis management mds
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Reticulocytes, MCV ... B12/Folate Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... Microcytic" • Iron ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... differential #diagnosis #causes
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... inflammation) • Iron ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined ... deficiencies
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Deficiencies: ... consumption • Vitamin B12 ... • Folate deficiency
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... • Dietary Deficiency ... and Folate Deficiency ... #Hematology
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery Nutrient Deficiencies: • Most frequent in the malabsorptive surgeries
, iron, B12 and ... • Persistent nausea ... years • Pervasive neurologic ... Phos, Ca+, Bl, B12 ... , Vit D, Folate,
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
: Iron deficiency ... loss), Vitamin B12 ... , Folate • Hormone ... deficiencies: Chronic ... , G6PD deficiency
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Micronutrient Deficiencies ... cardiomyopathy) • Folate ... • Vitamin B12 ... Trace Minerals: • Iron ... Bypass #vitamin #nutrition
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