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diagnosis treatment hydroxychloroquine sle adverseeffects anemia aplastic behcets benefits capsulatum cerebritis cns disease diuresis diuretics erythematosus excretion hematology histoplasma histoplasmosis
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... 200ng/mL Best indications ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... APS), Secondary prevention ... #rheumatology # ... cerebritis #diagnosis #management
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Hydroxychloroquine #hcq ... #pharmacology # ... #sideeffects #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... Topical steroids • Prevention ... #Treatment #management ... #pharmacology # ... rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... - CMV - HCV ... Anemia #oncology #hematology ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Kidney stones caused ... nocturnal enuresis • Prevention ... #Pharmacology # ... Medications #Table
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... lubricants • Pharmacologic ... #Rheumatology # ... Diagnosis #Management
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Recommendations for Preventing ... histoplasmosis (>10 cases ... BID for at least 12 ... #Treatment #management ... infections #HIVAIDS #pharmacology
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