7 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Induction Rx: high-dose ... #neurology #rheumatology ... cerebritis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... exacerbations: high-dose ... #diagnosis #management ... signs #symptoms #rheumatology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... Patchy areas of high ... The clinical syndrome ... dysfunction like gait ... dementia #AIDS #Neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Attempt if high ... effusions, weight gain ... Differential Diagnosis: Infection ... APML #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... pleural effusions, CNS ... blindness, or gait ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... DX relies on a high ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
fast bacterial infection ... Hypoalbuminemia Treatment ... Glucocorticoid, high ... TAFRO #diagnosis #management ... #rheumatology #