6 results
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... dysfunction (e.g. gait ... development of Korsakoff syndrome ... #Diagnosis #Management ... #neurology #nutrition
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... ; High-Ceiling Diuretics ... +CI- Symport - Thiazide ... Tolvaptan) • Treatment ... #Diuresis #Nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
compartment - b2 ... - Insulin (high ... Fanconi syndrome ... Furosemide - Thiazide ... differential #diagnosis #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Attempt if high ... effusions, weight gain ... Anaphylaxis, Acute Renal ... Supportive Care: Diuresis ... APML #diagnosis #management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
diuretic abuse ... • Hypokalemia (renal ... , Renal tubular ... Rhabdomyolysis Treatment ... #management #pathophysiology
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
12 hours prior ... alkalosis • Forced diuresis ... clearance but high ... #Toxicity #management ... #treatment #nephrology