15 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Induction Rx: high-dose ... #neurology #rheumatology ... #management #treatment
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Non-neuromuscular disorder ... pulmonary etc) • CNS ... endocrine: Vitamin B12 ... #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
and Management ... Diagnosis - Caine ... dysfunction (e.g. gait ... development of Korsakoff syndrome ... #Management #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Diagnosis: MRI ... Patchy areas of high ... The clinical syndrome ... dysfunction like gait ... dementia #AIDS #Neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... • Wide based gait ... , diaphoresis, high ... • High index of ... #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... oral ulcers in 12 ... exacerbations: high-dose ... #diagnosis #management
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... - Differential Diagnosis ... D-lactate (short bowel syndrome ... acidosis: - CNS ... #AcidBase #disorders
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... of injury • Gait ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... #diagnosis #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
fractures of feet, thigh ... membrane into the CNS ... Pernicious anemia/B12 ... respiratory failure • Neurologic ... ) - Waddling gait
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... bouts of HTN Diagnostic ... Check Vitamin B12 ... Deficiency: - Vitamin B12 ... #management #neurology