6 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Attempt if high ... effusions, weight gain ... coagulopathy, RRT ... APML #diagnosis #management ... #hematology #oncology
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Renal Replacement ... Therapy (RRT) - ... daily dialysis): ~12 ... High clearance achieved ... #managment #nephrology
Renal Replacement Therapy (RRT) Modalities

RRT Modalities in the ICU:
 • IHD (Intermittent HD):  3-5 hr
Renal Replacement ... RRT Modalities ... daily dialysis): ~12 ... High clearance achieved ... #managment #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... irrigation • Management ... Loop Diuretics; High-Ceiling ... Excretion #Diuresis #Nephrology ... #Pharmacology #
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
we introduce a high ... buffer against the drop ... The high CL- content ... #criticalcare #management ... diagnosis #treatment #pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ✔ If LVEF drops ... patients • LVEF 6-12 ... Cardiotoxicity #cardiology #oncology ... #pharmacology #