14 results
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders ... Hyperbilirubinemia == Disorders ... as jaundice on clinical ... with bilirubin encephalopathy ... • Disorder is
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Disorder (HAND) ... Neurocognitive disorders ... symptoms • Movement disorders ... syndrome of HAD ... neurocognitive #disorder
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Headache, Movement disorders ... , Seizure disorders ... Meningitis, Myelopathy, Encephalopathy
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... facial numbness), Encephalopathy ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... endocrine: Vitamin B12 ... • Inflammatory disorders ... Neoplastic: Malignancy-associated ... Differential #Diagnosis #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension associated ... with electrolyte disorders ... 109 mm Hg) with clinical ... Pregnancy-associated ... Neurologic disorders
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
men • Commonly associated ... Clinical Manifestations ... other neurological disorders ... limb or joint disorders ... Management #treatment #neurology
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
Hypertensive Disorders ... patients • HELLP: Syndrome ... Low platelets associated ... diagnosis so have high clinical ... #Hypertensive #Disorders
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... fluctuations PRES-Associated ... Seizures: Treat with AEDs ... #management #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... Associated with: ... Clinical Picture ... immunosuppressants - Meds ... diagnosis #management #neurology