17 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Vesicopustule on erythematous ... Discoid lupus erythematosus ... #differential #diagnosis
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
and Arthritis in Pediatrics ... - Differential Diagnosis ... migrans: • Target sign ... #differential #diagnosis ... #peds #pediatrics
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... Congenital Diseases ... Systemic lupus erythematosus ... consumption • Vitamin B12 ... #Hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... includes Kawasaki disease ... rash but without ... #Diagnosis #Dermatology ... Rash #Algorithm
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... - Neurological 12% ... #signs #symptoms ... #differential #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... neurology, back pain Haematology ... - Sickle cell disease ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Clinical features of Liver Disease in Children

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings #Diagnosis #Peds #Pediatrics #Hepatology

**
features of Liver Disease ... #LiverFailure #Signs ... PhysicalExam #Findings #Diagnosis ... #Peds #Pediatrics ... #Hepatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... severity of the disease ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... Petechial or purpuric rash ... systemic lupus erythematosus ... Activation #Syndrome #Diagnosis ... #Management #Hematology