43 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... thickening Signs ... and Symptoms: ... #diagnosis #signs ... #symptoms #testing
Sarcoidosis 
Systemic non-caseating granulomatous disease. 
Patients classically have mediastinal hilar lymphadenopathy. 
CXR is abnormal in 90%
Sarcoidosis Systemic ... granulomatous disease ... #Sarcoidosis #Signs ... #Symptoms #Diagnosis
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Clinical: • Disease ... exertion • Neurologic ... neuropathies • Skin ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Parkinson's Disease - Signs and Symptoms
Systemic: Tremor and Slowness, Impaired balance, Small Handwriting, Sleepiness, Trouble Moving
- Signs and Symptoms ... Systemic: Tremor ... : Constipation Skin ... #Signs #Symptoms ... #neurology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... Joint involvement- 12% ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Kawasaki Disease ... Syndrome) An rare systemic ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
erythematosus (SLE) Signs ... / Symptoms: - ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Common organ involvements and symptoms in Sarcoidosis
Lung 89-99% - Cough, dyspnoea, wheezing and stridor
Skin 16-32% -
in Sarcoidosis ... wheezing and stridor Skin ... vision loss Liver 12 ... pain Nervous system ... #diagnosis #signs