26 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Nikolsky's sign ... skin syndrome, caused ... #TEN #Dermatology ... #PhysicalExam #Video
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Is visual loss caused ... Clinical manifestations ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts ... #Management #dermatology
Relative Afferent Pupillary Defect

This maneuver of intermittent light stimulus is called the alternating light test or
It is a clear sign ... very sensitive diagnostic ... regarding the cause ... Pupillary #Defect #Neurology ... #Clinical #Video
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... ) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Presentation / Diagnosis ... : HLH signs and ... Diagnosis via genetic ... management #treatment #hematology
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
Asboe-Hansen sign ... or "Nikolsky II sign ... tool for diagnosing ... #PhysicalExam #Video ... #Blister #Dermatology