27 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Passive neck flexion causes ... spinal cord movement ... an involuntary reflex ... despite severe disease
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... gait, strength, reflexes ... superior iliac spine ... pathophysiology #differential ... #diagnosis #signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Cord Causes: 1 ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... Causes of spinal ... HIV) - Vitamin B12 ... in deep tendon reflexes ... #lesions #differential
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Strength, Normal Reflexes ... Other Congenital Syndromes ... - Spinal Cord ... #Peds #Pediatrics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... Signs / Symptoms ... of normal leg reflexes ... #signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... geriatrics #diagnosis #signs
Causes of Urinary Incontinence - Differential Diagnosis Algorithm
 - Transient - Easily reversible cause (DIAPPERS)
Incontinence - Differential ... Contraction - Signs ... neuropathy or spinal ... cord disease, cauda ... equina syndrome
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Pain (Otalgia) - Differential ... roots—cervical spine ... the following symptoms ... disease (GERD), ... • Associated symptoms
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... such as reflex ... carotid sinus syndrome ... syncope (ruling out differential ... orthostatic vital sign