22 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
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- Nail-fold changes ... or shawl sign ... gastroesophageal reflux ... Dermatomyositis #Diagnosis ... #Rheumatology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... gait, strength, reflexes ... superior iliac spine ... pathophysiology #differential ... #diagnosis #signs
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... flexion causes spinal ... an involuntary reflex ... despite severe disease ... PhysicalExam #Pediatrics #Peds
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... and signs below ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... dysfunction • Abnormal reflexes
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... and pepper" skin changes ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Chagas Disease - ... Trypanosomiasis - Diagnosis ... Romana's sign ... Indeterminate form (No signs ... /symptoms, positive
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
white matter, spinal ... oral ulcers in 12 ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... abdominojugular, reflux ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Check Vitamin B12 ... management #neurology #differential