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diagnosis management oncology dermatology syndrome rheumatology algorithm chronic cll differential lymphocytic skin alkaline alp antinxp2 antinxp2dm aplastic bacilliformis bandemia bartonella
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... - infiltrates (anemia ... violaceous, nontender cutaneous ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... to IBD, celiac disease ... Check for IF ab Treatment ... diagnosis e.g. leukemia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... involvement (2%) Cutaneous ... • Severe Liver Disease ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Episcleritis Signs ... Causes: - Idiopathic ... Treatment: - Systemic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
vasculitis) • Cutaneous ... oral ulcers in 12 ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... diagnosis #management #signs
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Syndromes #diagnosis #hematology
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