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Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Congenital Diseases ... consumption • Vitamin B12 ... deficiency Infections ... #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Inflammation, Chronic Infection ... (>100 fL) • B12 ... Classification #Differential ... Algorithm #Causes #Hematology
Hand, Foot, and Mouth Disease: A febrile illness (caused by Coxsackie Virus) associated vesicle formation on
Foot, and Mouth Disease ... UCSD Catalog of Clinical ... Images #Clinical ... #Dermatology #Pediatrics ... Vesicle #UCSDH #Photo
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection Malar ... infection • Lyme ... disease • Rosacea ... Sarcoidosis #dermatology ... #skin #rashes #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... Macroangiopathic, Infections ... Folate deficiency, B12 ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - Differential ... Viral: Measles, Infectious ... HIV, Parvovirus B19 ... gonorrhea, Rickettsial diseases ... #Diagnosis #dermatology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
upper respiratory infection ... Syndrome #SSSS #Clinical ... #Photo #Peds #Pediatrics ... #Dermatology