38 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
associated with infection ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... steroids to treat infectious ... diseases - Severe ... #Pharmacology # ... Management #Treatment
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Diagnosis, causes and management ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... with refractory disease ... Cryoglobulinemic #Diagnosis #Management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Diaqnoses: • Infectious ... #diagnosis #management ... #treatment #rheumatology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... the Management ... blood cell count (<12 ... oral antibiotic treatment ... or those with clinical
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
of COVID-19 Infection ... Even with macular disease ... highlighted circle= clinical ... #COVID19 #Pharmacology ... #Table #Management
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... underlying liver disease ... Coagulation Failure Infections ... Failure #Cirrhosis #Hepatology