47 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... underlying liver disease ... Coagulation Failure Infections ... #Hepatology #gastroenterology
Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology ... #anemia #clinical
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm Infectious ... Congestive • Cirrhosis ... • Sickle Cell ... Disease (children ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... • Clinical features ... Etiology: - Infections ... Lymphomas • Other hematologic ... #differential #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Colitis and Crohn’s Disease ... Diabetes/DKA Infections ... : • helminth infections ... Irradiation • Cirrhosis ... Diagnosis #causes #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... lymphoid malignancy (CLL ... Clinical Presentation ... malignancies -> CLL ... hemolytic #anemia #hematology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
• HIV/HCV co-infection ... or fibrosis • Cirrhosis ... ) • Use of B-cell ... • Acute HBV infection ... Indications #management #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
loss), Vitamin B12 ... Chronic kidney disease ... (e.g. cancer, infection ... defects (e.g. sickle cell ... Production #Index #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... immunophenotype Clinical ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology