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diagnosis differential management algorithm oncology syndrome workup bleeding classification dvt thrombocytosis cancer hemolytic mcv pancytopenia thromboembolism venous aplastic breakthrough bruising
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
- Behcet's disease ... Structural - Pelvic masses ... Recurrent #DVT #VTE ... #anticoagulation ... #hematology #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... deficiency: • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... Non-infectious (malignancy, rheumatologic ... Chronic Myeloid Leukemia ... Differential #Diagnosis #causes ... #Platelets #hematology
Algorithm for the Long-Term Treatment of Venous Thromboembolism Reference: https://doi.org/10.1182/blood.2019002364 by Dr. Clive Kearon and Dr. Susan
the Long-Term Treatment ... #LongTerm #Treatment ... Thromboembolism #VTE ... #Anticoagulation ... #Algorithm #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Cancer: • Leukemia ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
) and IMPROVE (VTE ... validated for VTE ... treatment, only ... of withholding anticoagulation ... #Factors #Hematology
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