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differential causes management lfts syndrome classification hepatitis injury transaminitis workup ascites chronic gastroenterology macrocytic mcv rheumatology abnormal atlas dermatology fatty
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Hypothyroid • Liver ... Disease • Alcohol ... #differential #diagnosis ... #algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... Renal Disease, Liver ... (>100 fL) • B12 ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Pancreatic Disease ... #Algorithm #Causes ... #Hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... 100-500): • NAFLD ... • Cirrhosis ... Hepatopathy • Acute ... #hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... • Cholestatic disease ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... chronic kidney disease ... - Vitamin B12 ... Underproduction #Algorithm ... #hematology #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Folate deficiency, B12 ... Non-megaloblastic: Liver ... disease, Alcoholism ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... #Hepatology #gastroenterology ... #management #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Macrocytic RBC: Vitamin B12 ... Folate deficiency, Liver ... , Liver disease, ... #differential #diagnosis ... #hematology #microscopy
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