28 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Renal Disease, Liver ... (>100 fL) • B12 ... Reticulocytosis • Liver ... #MCV #Classification ... Algorithm #Causes #Hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
812, Folate ... Hypothyroid • Liver ... Disease • Alcohol ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Macrocytic RBC: Vitamin B12 ... Folate deficiency, Liver ... , Liver disease, ... stomatocytosis, Liver ... differential #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Low Serum B12 ... - Low Serum B12 ... • Pancreatic Disease ... Disease #Macrocytic ... Algorithm #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... ALT < 5x ULN • NAFLD ... • Cholestatic disease ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Non-Alcoholic Fatty Liver Disease (NAFLD) Progression / Prognosis Timeline
 • 100 patients → (over 20+ years)
Non-Alcoholic Fatty Liver ... Disease (NAFLD) ... NonAlcoholic #FattyLiver #Disease ... #NAFLD #Progression ... Prognosis #Timeline #Hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... Folate deficiency, B12 ... Non-megaloblastic: Liver ... disease, Alcoholism ... Differential #Diagnosis #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... disease, liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Megaloblastic: Vitamin B12 ... : Alcohol use, Liver ... disease (independent ... diagnosis #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology