52 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... pathophysiology #pbc ... #psc #hepatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
: Vitamin B12 or ... Folate deficiency, Liver ... , Liver disease, ... stomatocytosis, Liver ... differential #diagnosis #hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Wilson's, HH, NAFLD ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Algorithm #diagnosis #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Neutrophils - Low RBC ... - Low Serum B12 ... • Pancreatic Disease ... Disease #Macrocytic ... Algorithm #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
812, Folate ... Hypothyroid • Liver ... Disease • Alcohol ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Antitrypsin • Other: NAFLD ... Syndrome, Celiac Disease ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Acute #algorithm #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... (>100 fL) • B12 ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Spherocytosis, G6PD, PK, HbC ... Folate deficiency, B12 ... Non-megaloblastic: Liver ... disease, Alcoholism ... Differential #Diagnosis #hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... of autoimmune disease ... Liver biopsy findings ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology