71 results
differential management algorithm anemia causes syndrome dermatology gastroenterology hemolysis monoclonal acute chronic cirrhosis classification hemeonc hemophagocytic hlh injury leukemia liver
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Increased red cell ... Increased red cell ... Differential #Causes #Workup ... #Hematology #Diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... organ or stem cell ... crisis • Severe B12 ... #differential #diagnosis ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... cold agglutin disease ... #differential #diagnosis ... #hematology #anemia
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... telomeropathy Cancer ... Antibody-mediated hemolysis ... consumption • Vitamin B12 ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Consider sickle cell ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Macrocytic Anemia • 812 ... Hypothyroid • Liver Disease ... #differential #diagnosis ... #algorithm #hematology ... #workup
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Macrocytic RBC: Vitamin B12 ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... #differential #diagnosis ... #hematology #microscopy
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Underproduction Diagnostic ... chronic kidney disease ... - Vitamin B12 ... Underproduction #Algorithm #hematology ... #workup
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