10 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... -> AML: Blast crises ... - infiltrates (anemia ... #Hematology #Oncology
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... Primary: Lymphoma, Leukemia ... #cardiology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... to manifest its symptoms ... , alcohol use, symptoms ... Check for IF ab Treatment ... diagnosis e.g. leukemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... Treatment: ... • Improve the symptoms ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... skin that are caused ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Nutritional: vitamin B12
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
oral ulcers in 12 ... Oral aphthae : SLE ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... #rheumatology #
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
14%), in which case ... enzymes ↑ • Mild anemia ... • New onset SLE ... detecting HIV for 10-12 ... antibody test) Treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Treat underlying cause ... interventional radiology ... Usually myeloid leukemias ... treat - Calcium > 12 ... → no immediate treatment