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diagnosis management hematology anemia chronic mds myelodysplastic aclf acute algorithm aplastic apml differential differentiation failure hemochromatosis hepatopulmonary hps leukemia liver
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... (± cirrhosis) w ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Renal Failure Treatment ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Parvovirus B19 ... • Parvovirus B19 ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia in Cirrhosis ... PRODUCTION • Vitamin B12 ... Destruction: Zieve's syndrome ... , Spur cell anemia ... Differential #Diagnosis #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
diagnosis and treatment ... Step 3: All patients ... Patients with cirrhosis ... diagnosis #management #hepatology ... #gastroenterology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... primary biliary cirrhosis ... Cryoglobulinemia (4%-12% ... lymphoma • B cell ... Adenocarcinoma Treatment
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
• Stigmata of cirrhosis ... the left heart TREATMENT ... mortality rate of ~12% ... #cirrhosis #diagnosis ... #hepatology
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