16 results
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Platelet Disorders • Nutritional ... : vitamin B12 or ... #diagnosis #hematology ... #oncology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... diagnosis #signs #symptoms ... #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... • Improve the symptoms ... #oncology #hematology
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... Haematological: Anaemia ... #riskfactors #symptoms
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... to manifest its symptoms ... , alcohol use, symptoms ... Check for IF ab Treatment ... diagnosis #management #nutrition
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
of anemia or thrombocytopenia ... marrow failure with anemia ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc