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diagnosis differential oncology pancytopenia acidosis aplastic approach chronic cll elevatedmcv elevation infections infectiousdiseases lactate lactic leukemia lymphocytic macrocytic macrocytosis management
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... Toxins • Aplastic Anemia ... deficiency: • B12 ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... (>100 fL) • B12 ... #MCV #Classification ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... Myelodysplastic Syndromes ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Deficiency • B12 ... #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Difficulty breathing • Neutropenia ... and petechiae Causes ... - Parvovirus B19 ... Treatment: ... #oncology #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... hypertension and/or drug treatment ... , Kostmann syndrome ... Megaloblastic anemia-rare ... #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... hemoglobin of less than 12 ... primarily seen as neutropenia ... These causes could
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Myeloproliferative Disease • Neutropenia ... Nutritional: vitamin B12 ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... microglobulin Treatment ... workup #oncology #hematology
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