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diagnosis management symptoms differential erythematosus lupus mds myelodysplastic systemic aplastic autoantibodies behcet chronic cll disease leukemia lymphocytic macrophage mas mimickers
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... diagnosis: 70 years old ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anticonvulsants - Gold ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Neurological 12% ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... autoantibodies #signs ... #differential #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
oral ulcers in 12 ... Oral aphthae : SLE ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
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