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diagnosis management algorithm oncology deficiency rheumatology signs symptoms cirrhosis classification hemeonc hepatology infectiousdiseases neutropenia pancytopenia table thrombocytopenia vitamin acidosis aplastic
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Pancytopenia - Differential ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... Vitamins #Deficiency #differential ... signs #symptoms #nutrition
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Myelodysplastic Syndromes ... #elevatedMCV #Differential ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Malaria, babesia - Nutritional ... : B12, copper, folate ... antiphospholipid syndrome ... Diagnosis #Framework #hematology
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... ataxia), Korsakoff syndrome ... • Vitamin B12 ... Bypass #vitamin #nutrition ... #table #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... - Parvovirus B19 ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Platelet Disorders • Nutritional ... : vitamin B12 or ... blood count with differential ... #diagnosis #hematology
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