20 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Vesicopustule on erythematous ... Discoid lupus erythematosus ... #dermatology #joint ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... Systemic #Lupus #Erythematosus ... diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... Systemic lupus erythematosus ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Lyme Disease: Clinical diagnosis. Likely if recent hiking, travel to endemic area, erythema migrans (EM), an
migrans (EM), an erythematous ... Treatment is doxycycline ... skin, joints, or ... carditis, meningitis (see ... #LymeDisease #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... pain (20%) Renal disease ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Neurological 12% ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #differential #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... Systemic Lupus Erythematosus ... Evolution: Chronic disease ... comparison #table #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
constitutional symptoms ... - Autoimmune Rheumatologic ... • Parvovirus B19 ... arthritis • SLE ... Symmetrical: • RA • SLE
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... Systemic lupus erythematosus ... (SLE) - Antinuclear ... diagnosis #testing #Rheumatology