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diagnosis management hematology differential syndrome erythematosus leukemia systemic chronic dermatology hivaids idsa joint lymphocytic nephrology opportunistic pain prevention workup activation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... /SLL into a significantly ... #Oncology #Diagnosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection Malar ... rash • SLE ... infection • Lyme ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Neurological 12% ... involvement 3% SLE-Related ... Other auto-immune, Infectious ... Lupusreference #SLE ... #differential #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... Vasculitides: Giant Cell ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... #table #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... weeks without infection ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... : • Chronic B-cell ... Erythematosus #Diagnosis #Rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... 0.5-0.7 g/g by 12 ... Nephritis #Management #treatment ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Unknown cause Treatment ... #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Complications: 1) Infection ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
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