28 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection Malar ... rash • SLE ... infection • Lyme ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... Other auto-immune, Infectious ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... erythematosus (SLE ... : Lupus (SLE), Systemic ... Lymphoproliferative Disorders, Infection ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... - Autoimmune Rheumatologic ... • Parvovirus B19 ... arthritis • SLE ... Symmetrical: • RA • SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... erythematosus [SLE ... ], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... ), RA, crystal disease ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology #
Holistic Management of Systemic Lupus
 • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
fatigue, Fibromyagia/pain ... Cardiovascular risk, Infection ... #holistic #SLE ... Erythematosus #management #treatment ... #rheumatology