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hematology differential clinical algorithm causes management oncology deficiency rash rheumatology secondary signs skin pancytopenia symptoms systemic workup abnormal acidosis classification
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Petechiae: punctate spots that arise from spontaneous bleeding secondary to profound thrombocytopenia. The spots (easily visible
Petechiae: punctate spots ... The spots (easily ... non-blanching and non-tender ... Images #Clinical #Photo ... #Dermatology #Rash
Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
a Reticulocyte Index ... ) Reticulocyte Index ... #Reticulocyte #Index ... #RI #RPI #hematology ... #diagnosis #anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... for degree of anemia ... thecurbsiders podcast #Anemia ... #Algorithm #Diagnosis ... #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production Index ... appropriately)- Retic Index ... appropriately) - Retic Index ... #hematology #anemia ... #differential #diagnosis
Staphylococcal Scalded Skin Syndrome (SSSS) A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded Skin Syndrome ... patient’s rash is tender ... Scalded #Skin #Syndrome ... SSSS #Clinical #Photo ... Peds #Pediatrics #Dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • Reticulocyte index ... #oncology #hematology ... #diagnosis #management
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... for Anemia (Morphological ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology
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