14 results
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
- Summary Table ... are beta blockers ... - Potassium Channel ... Blockers Class ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... #causes #potassium ... #low #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... TTKG should be high ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
inhibitors Other causes ... transplant - SLE High ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... differential #diagnosis #causes ... #potassium #high
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... - When digoxin blocks ... intracellular calcium causes ... Hyperkalemia (high ... Since digoxin blocks
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... • ENaC blockers ... nephropathy • Beta ... #Causes