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diagnosis differential causes hyperkalemia nephrology pharmacology cardiology antiarrhythmics hypokalemia acg achalasia antiarrhythmic clinicopathology digoxin disorders gastroenterology guidelines hematology intercellularshift laboratory
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table Class I agents - Sodium Channel Blockers⠀ Class II
- Summary Table ... are beta blockers ... - Potassium Channel ... Blockers Class ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... #potassium #high
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... TTKG should be high ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... #potassium #high
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... transplant - SLE High ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... - When digoxin blocks ... intracellular calcium causes ... Hyperkalemia (high ... Since digoxin blocks
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... age range • High ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
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