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diagnosis differential causes hyperkalemia pharmacology high nephrology cardiology hypokalemia management low antiarrhythmics medications summary treatment acg achalasia angiotensin antiarrhythmic arb
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table Class I agents - Sodium Channel Blockers⠀ Class II
- Summary Table ... are beta blockers ... - Potassium Channel ... Blockers Class ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Release: NSAIDs, Beta-Blockers ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium
Bradycardia Diagnostic and Management Algorithm CONSIDER ETIOLOGY (not inclusive): - STRUCTURAL: sick sinus, AV block, ischemia,
and Management Algorithm ... Hypothyroidism - TOX: beta-blockers ... LIFE THREATENING CAUSES ... TREATMENT - Drugs (beta-blockers ... #Bradycardia #Algorithm
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Classes #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
inhibition (NSAIDs, Beta-Blockers ... Angiotensin II Receptor Blockers ... Sodium-channel blockers ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Differential Diagnosis Algorithm ... Alkalosis • ↑ beta ... : • GI losses ... Differential #Diagnosis #Algorithm ... nephrology #low #potassium
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
- Anorexia GI Losses ... Ureterosigmoidostomy Urinary Losses ... Diagnosis #Low #Potassium ... #Table #Classification ... #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... adrenergic receptor blockers ... #potassium #high
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