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diagnosis causes hepatology dermatology hematology ddxof primary anemia liver management nephrology rash disorders lfts pbc pediatrics peds pruritus rheumatology workup
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... Duct Stone • Biliary ... #LiverEnzymes #Differential ... #Diagnosis #Algorithm
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Pool → ↑ Hepatic Bile ... Plasma LDL-C #biliary ... sequestration #pathophysiology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... genes coding for bile ... external pressure on bile ... #Jaundice #Classification ... #unconjugated #differential
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... gradual loss of bile ... inflammation and biliary ... #PBC #Primary #Biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... PSC - Other biliary ... diseases/Bile duct ... #Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... • US - Normal Bile ... - CBD stone, Biliary ... Transaminitis #Algorithm
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... No extrahepatic biliary ... ducts Differential ... malignancy #Primary #Biliary
Congenital Heart Disorders - Classification and Differential Algorithm - Amy Chung, MD, MSc @AmyChung #Congenital #Heart #Disorders
Heart Disorders - Classification ... and Differential ... Algorithm - ... #Differential # ... Algorithm #Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... usually at a single site ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... on Ultrasound Biliary ... Gallstones • Biliary ... #Diagnosis #Algorithm
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