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hematology management differential oncology anemia chronic classification cll leukemia lymphocytic syndromes thrombocytopenia aplastic apml cancer causes cell criteria cryofibrinogenemia differentiation
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... glucocorticoid treatment ... #diagnosis #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Algorithm Features ... /bleeding, fatigue ... predominant immature cells ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... - History of bleeding ... pylori test (GI symptoms ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... Responsive to Treatment
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... cells - Consider ... Consider RBC membrane disorder ... #Algorithm #workup
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... age 70 years Symptoms ... are caused by bleeding ... Myelodysplastic #Syndromes #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... & DIAGNOSIS Labs ... or serologies + symptoms ... capillaritis leading ... #management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... lymphoproliferative disorders ... microglobulin Treatment ... #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... Renal Failure Treatment
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