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hematology oncology management mds myelodysplastic algorithm atlas cancer cell chronic classification cll differential emergencies hemeonc hodgkins key leukemia lymphocytic lymphoma
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Treatment: • Consider ... #Anemia #diagnosis ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... anemia Treatment ... #hematology #diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Sickle cells ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... Simultaneous clotting and bleeding ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... EMD myeloma Diagnostic ... Bone marrow Treatment ... #Workup #Hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... median age at diagnosis ... cardiovascular or pulmonary ... disease tolerate anemia ... an infection or bleeding
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