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diagnosis management gastroenterology ibs irritable anemia aplastic apml differential differentiation emergencies hemeonc immune inflammatory iris leukemia mds myelodysplasia myelodysplastic oncologic
Irritable Bowel Syndrome (IBS) - Management Global IBS Symptoms: - Limited trial low FODMAP diet
Irritable Bowel ... Syndrome (IBS) - ... Secretagogues → activate ... intestinal epithelial cells ... gastroenterology #treatment
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel ... Syndrome (IBS) - ... for diagnosis Treatment ... Secretagogues → activate ... IBS #Irritable #Bowel
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Simultaneous clotting and bleeding ... urinary retention, bowel ... “big & sticky” cells ... renal failure, pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... muscarinic agonists • Active
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... serositis peritonitis, bowel ... • Persistently active ... #Inflammatory #Syndrome
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