12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... involvement CML (Chronic ... lymphoid organs When Cancer ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- History of Bleeding ... Age > 50 • Chronic ... Reed-Sternberg Cells ... Algorithm #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... lymphocytes, smudge cells ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Silicosis • Chronic ... Lymphoma • Lung cancer ... involvement - seeding ... malignancy, and chronic ... Tuberculosis Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Silicosis • Chronic ... Lymphoma • Lung cancer ... involvement - seeding ... malignancy, and chronic ... Tuberculosis Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Simultaneous clotting and bleeding ... Usually myeloid leukemias ... “big & sticky” cells ... renal failure, pulmonary
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
pneumonia • Chronic ... • Large volume feeding ... foreign body, cancer ... westermani • Other: TB ... Lung #Abscess #pulmonary