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diagnosis management algorithm mds myelodysplastic anemia aplastic apml cancer chf chronic clinical cll criticalcare differential differentiation emergencies foamed heartfailure hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Simultaneous clotting and bleeding ... Usually myeloid leukemias ... “big & sticky” cells ... renal failure, pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... causing hypovolemia needing ... acute coronary syndrome ... algorithm #management #cardiology ... #treatment #table
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment ... acute myeloid leukemia ... cardiovascular or pulmonary ... an infection or bleeding ... #algorithm #hematology
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