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diagnosis management oncology differential rheumatology cardiology signs symptoms table algorithm anemia aplastic apml cardiomyopathy coagulation comparison contusion criticalcare cryofibrinogenemia ctchest
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Findings: • Bleeding ... Treatment: ... Treat primary cause ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... common • Imaging: CXR ... - pulmonary opacities ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Pathogenesis and clinical ... findings Patients ... PO4& Mg prior to feeding ... overload -> - CHF ... - Pulmonary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... by bleeding (petechiae ... factors (examples: G-CSF ... #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : Age>60, CKD, CHF ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... lymphadenopathy CML Findings ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Leukemia #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... symptoms are not caused ... e.g. incidental CXR ... finding) ... Pulmonary: dyspnea
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Rule out other causes ... • Laboratory findings ... , breast bone, pelvis ... and lower jaw Treatment
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